Esomeprazole injection is used to treat gastroesophageal reflux disease (GERD; a condition in which backward flow of acid from the stomach causes heartburn and possible injury of the esophagus [the tube between the throat and stomach]) in adults and children 1 month of age or older who have had damage to their esophagus and are unable to take esomeprazole by mouth.
Esomeprazole injection is also used in adults to reduce the risk of further ulcer bleeding after an endoscopy (examination of the inside of the esophagus, stomach, and intestines). Esomeprazole is in a class of medications called proton pump inhibitors. It works by decreasing the amount of acid made in the stomach.
Esomeprazole injection comes as a powder to be mixed with liquid and given intravenously (into a vein) by a doctor or nurse in a medical facility. For the treatment of GERD, esomeprazole is usually given intravenously once a day. For the prevention of re-bleeding after an endoscopy, esomeprazole injection is usually given as a continuous intravenous infusion for 72 hours.